Updated May 29, 2019
| AL East | Closer | Job security | Tier | Next up | Wild card |
| Baltimore Orioles | Shawn Armstrong (committee) | + | 5 | Paul Fry | Miguel Castro |
| Boston Red Sox | Matt Barnes (committee) | + | 3 | Ryan Brasier | Tyler Thornburg |
| New York Yankees | Aroldis Chapman | +++ | 1 | Zach Britton | Adam Ottavino |
| Tampa Bay Rays | Jose Alvarado (committe) | ++ | 3 | Diego Castillo | Emilio Pagan |
| Toronto Blue Jays | Ken Giles | ++ | 3 | Joe Biagini | Ryan Tepera |
| AL Central | |||||
| Chicago White Sox | Alex Colome | ++ | 3 | Kelvin Herrera | Jace Fry |
| Cleveland Indians | Brad Hand | +++ | 2 | Nick Wittgren | Adam Cimber |
| Detroit Tigers | Shane Greene | ++ | 2 | Joe Jimenez | Victor Alcantara |
| Kansas City Royals | Ian Kennedy (committee) | + | 5 | Jake Diekman | Brad Boxberger |
| Minnesota Twins | Blake Parker (committee) | ++ | 4 | Taylor Rodgers | Trevor May |
| AL West | |||||
| Houston Astros | Roberto Osuna | +++ | 1 | Ryan Pressly | Hector Rondon |
| Los Angeles Angels | Hansel Robles (committee) | + | 4 | Ty Buttrey | Cody Allen |
| Oakland Athletics | Blake Treinen | +++ | 2 | Lou Trivino | Joakim Soria |
| Seattle Mariners | Roenis Elias (committee) | + | 5 | Brendon Brennan | Hunter Strickland (Inj) |
| Texas Rangers | Shawn Kelley | + | 5 | Jose Leclerc | Chris Martin |
| NL East | |||||
| Atlanta Braves | Luke Jackson | + | 4 | Sean Newcomb | AJ Minter |
| Miami Marlins | Sergio Romo (committee) | + | 5 | Adam Conley | Tayron Guerrero |
| New York Mets | Edwin Diaz | +++ | 1 | Jeurys Familia | Robert Gsellman |
| Philadelphia Philles | Hector Neris (committee) | ++ | 3 | Juan Nicasio | David Robertson (inj) |
| Washington Nationals | Sean Doolittle | +++ | 2 | Wander Suero | Justin Miller |
| NL Central | |||||
| Chicago Cubs | Steve Cishek | + | 4 | Pedro Strop | Brandon Morrow (inj) |
| Cincinnati Reds | Raisel Iglesias | +++ | 3 | Jared Hughes | David Hernandez |
| Milwaukee Brewers | Josh Hader | +++ | 1 | Jeremy Jeffress | Junior Guerra |
| Pittsburgh Pirates | Felipe Vazquez | +++ | 2 | Kyle Crick | Keone Kela (inj) |
| St Louis Cardinals | Jordan Hicks | ++ | 2 | Andrew Miller | Carlos Martinez |
| NL West | |||||
| Arizona Diamondbacks | Greg Holland | ++ | 3 | Yoshihisa Hirano | Archie Bradley |
| Colorado Rockies | Scott Oberg | + | 4 | Bryan Shaw | Wade Davis (inj) |
| Los Angeles Dodgers | Kenley Jansen | +++ | 1 | Pedro Baez | Joe Kelly |
| San Diego Padres | Kirby Yates | +++ | 2 | Craig Stammen | Adam Warren |
| San Francisco Giants | Will Smith | +++ | 3 | Tony Watson | Reyes Moranta |